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Rheumatoid Arthritis TNF inhibitors reduce fatigue

Rheumatoid Arthritis: TNF Inhibitors Linkedto Less Fatigue Lara Pullen writing for Medscape reportedon a study demonstrating patients with rheumatoid arthritis (RA) report substantial improvementof fatigue after beginning anti–tumor necrosis factor α (TNFα) therapy. In particular,employed women with a low level of disability were the most likely to experience an improvementin fatigue. Pain, however, was not a significant predictor of improvement in fatigue.Although fatigue is generally considered a significant factor in RA, it is rarely a primaryendpoint in al trials. Katie L. Duce, a PhD student from the Epidemiology Group,Institute of Applied Health Sciences, University

of Aberdeen, United Kingdom, and colleaguespublished the results of their longterm observational cohort study in the journal, Rheumatology.Comment: Second only to pain and stiffness, fatigue is a major problem for patients withRA. In my experience, TNF inhibitors are great at reducing fatigue.

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